alzheimer's disease radiology, symtoms /signs and it,s treatment

 Alzheimer's disease radiology , commonly known as Alzheimer's disease, Alzheimer's disease, and dementia, is a slow course of onset and continuous over time A worsening neurodegenerative disease, which accounts for 60% to 70% of dementia

 As the alzheimer's disease radiology progresses gradually,

symptoms may gradually appear, including language disorder (English: primary progressive aphasia), disorientation (English: Orientation (mental)) (Including easy to get lost), emotional instability (English: mood swing), loss of motivation, inability to take care of oneself, and many behavior problems (English: challenging behaviour).

When the situation worsens, the patient will often become disconnected from the family or society [1], and gradually lose physical function, eventually leading to death.

 Although the course of the disease varies from person to person, the average remaining life after diagnosis is about three to nine years.

Alzheimer disease
Synonym
Alzheimer's disease
Alzheimer's disease brain comparison-zh.jpg
Compare the brains of normal (left) and Alzheimer's disease (right) patients.

symptom

Short-term memory loss, language impairment (English: primary progressive aphasia), disorientation (English: Orientation (mental)), mood swing (English: mood swing)[1][2]
Commonly originated in
Over 65 years old [3]
Course of disease
Chronic [2]

Types of
Abnormal deposition of Tau protein[*], aging-related diseases[*]

Cause

Limited understanding [1]
Risk factor
Heredity, head trauma, depression, high blood pressure[1][4]
diagnosis method
After excluding other possible causes, diagnosis based on symptoms and cognitive tests (English: cognitive test) [5]
Similar diseases or comorbidities
Normal aging [1]
drug Acetylcholinesterase inhibitor, NMDA receptor antagonist (slightly helpful) [6]

Prognosis

3 to 9 years remaining [7]
Prevalence
29.8 million people (2015)
Number of deaths
1.9 million people (2015)
Classification and external resources
Medical Specialty
Neurology
ICD-9-CM
331.0, 290.1
OMIM
615590, 615711, 605526
DiseasesDB
490
MedlinePlus
000760
eMedicine
1134817
Patient UK (English: Patient UK)
Alzheimer disease
[Edit Wikidata for this entry]
China Mainland
Alzheimer's disease[8]
Taiwan

Alzheimer's disease radiology

The true cause of Alzheimer's disease is still unknown [1]. At present, Alzheimer’s disease is regarded as a neurodegenerative disease, and it is believed that nearly 70% of the risk factors are genetically related [4]; other risk factors include head trauma, depression, and hypertension [1] . The course of the disease is related to the deposition of fibrous amyloid protein plaques (English: Senile plaques) and Tau protein in the brain [4]. To diagnose Alzheimer's disease, other possible factors need to be ruled out based on the patient's medical history, behavioral assessment, cognitive tests (English: Cognitive tests), brain imaging examinations, and blood tests [5]. Symptoms at the beginning of the disease are often mistaken for normal aging [1]. The diagnosis requires the help of brain tissue examination [4]. Mental exercise (English: Mental exercise), physical exercise, and avoiding obesity can all help reduce the risk of Alzheimer's disease[4][11]. There is currently no evidence to prove that specific drugs or nutritional supplements are effective in treating diseases [12].

At present, there is no treatment that can prevent or reverse the course of the disease, and only a few methods may temporarily relieve or improve symptoms [2]. Illness will make patients need more and more care from others (English: Caring for people with dementia), which is a great burden for caregivers; such care pressure encompasses social, physical, spiritual, and economic levels[13 ]. Exercise planning can improve the patient's daily life functions and may improve the prognosis [14]. Behavioral abnormalities and psychiatric disorders caused by dementia symptoms are often treated with antipsychotics, but their effectiveness is not high and may increase mortality, so it is generally not recommended to use [15] [16].

In 2015, approximately 29.8 million people worldwide suffered from Alzheimer's disease[2][17]. The age of onset of patients is generally over 65 years old, but about 4% to 5% of patients will develop the disease before the age of 65, which is early-onset Alzheimer's disease (English: Early-onset Alzheimer's disease) [3]. The prevalence rate over 65 years old is about 6% [1]. In 2015, dementia caused approximately 1.9 million deaths [18]. In 1906, German psychiatrist and pathologist Alois Alzheimer first described and then named Alzheimer's disease [19]. In developed countries, Alzheimer's disease is a disease that consumes the most social resources[20][21].